The objective of this study was to determine the effect of an intensive nurse home visiting program on a composite outcome of preterm birth, low birth weight, small for gestational age, or perinatal mortality. In this South Carolina–based trial of Medicaid-eligible pregnant individuals, assignment to participate in an intensive nurse home visiting program did not significantly reduce the incidence of a composite of adverse birth outcomes. Evaluation of the overall effectiveness of this program is incomplete, pending assessment of early childhood and birth spacing outcomes.


  1. Moniz MH, Low LK, Stout MJ. Intensive Nurse Home Visiting Program and Adverse Birth Outcomes. JAMA. 2022 Jul 5;328(1):23-4.

  2. McConnell MA, Zhou RA, Martin MW, Gourevitch RA, Steenland M, Bates MA, Zera C, Hacker M, Chien A, Baicker K. Protocol for a randomized controlled trial evaluating the impact of the Nurse-Family Partnership’s home visiting program in South Carolina on maternal and child health outcomes. Trials. 2020 Dec;21(1):1-21.

  3. Mallampati D, Jackson C, Menard MK. The association between care management and neonatal outcomes: the role of a Medicaid-managed pregnancy medical home in North Carolina. American Journal of Obstetrics and Gynecology. 2022 Mar 10.


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