The authors aimed to assess the safety and clinical effectiveness of intravenous iron sucrose (intervention) versus standard oral iron (control) therapy in the treatment of women with moderate-to-severe iron deficiency anaemia in pregnancy. The study was stopped due to futility. There is insufficient evidence to show the effectiveness of intravenous iron sucrose in reducing clinical outcomes compared with standard oral iron therapy in pregnant women with moderate-to-severe anaemia.
Peña-Rosas JP De-Regil LM Garcia-Casal MN Dowswell T. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2015; 7CD004736
Perewusnyk G Huch R Huch A Breymann C. Parenteral iron therapy in obstetrics: 8 years experience with iron-sucrose complex. Br J Nutr. 2002; 88: 3-10
Shi Q Leng W Wazir R et al. Intravenous iron sucrose versus oral iron in the treatment of pregnancy with iron deficiency anaemia: a systematic review. Gynecol Obstet Invest. 2015; 80: 170-178