This study is a a multicenter, noninferiority, randomized, controlled trial involving women requesting medication abortion at up to 42 days of gestation with an unconfirmed intrauterine pregnancy on ultrasound examination (visualized as an empty cavity or a sac-like structure without a yolk sac or embryonic pole). Findings sugget that medication abortion before confirmed intrauterine pregnancy was noninferior to standard, delayed treatment with respect to complete abortion.

https://pubmed.ncbi.nlm.nih.gov/39504520/

References

  1. Borchert K, Thibodeau C, Varin P, Wipf H, Traxler S, Boraas CM. Medication abortion and uterine aspiration for undesired pregnancy of unknown location: a retrospective cohort study. Contraception 2023;122:109980-109980.

  2. Schreiber CA, Creinin MD, Atrio J, Sonalkar S, Ratcliffe SJ, Barnhart KT. Mifepristone pretreatment for the medical management of early pregnancy loss. N Engl J Med 2018;378:2161-2170.

  3. Whitehouse KC, Stifani BM, Duffy JMN, et al. Standardizing abortion research outcomes (STAR): results from an international consensus development study. Contraception 2021;104:484-491.

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Maternal/Fetal health during pregnancy  

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